Wissenschaft

Die Studienlage zu Nahrungsergänzungsmitteln zeigt:

Richtig eingesetzt, können sie eine wertvolle Ergänzung zu einer ausgewogenen Ernährung sein. Wissenschaftliche Untersuchungen bestätigen die Wirksamkeit bestimmter Nährstoffe für Gesundheit, Energie und Wohlbefinden. Entscheidend ist jedoch Qualität, Dosierung und eine fundierte Grundlage. Hier findest du eine Auswahl an Studien, die wir bei der Entwicklung unserer Produkte berücksichtigt haben.



Haarausfall

  • Almohanna HM et al. (2018). The role of vitamins and minerals in hair loss: a review. Dermal Ther (Heidelb) 9(1):51-70.
  • Guo EL and Katta R (2017). Diet and hair loss: effects of nutrient deficiency and supplement use. Dermatology Practical & Conceptual 7:1-10.
  • Kil MS, Kim CW and Kim SS (2013). Analysis of serum zinc and copper concentrations in hair loss. Ann Dermatol 25(4):405-409.
  • Panahi Y et al. (2025). Rosemary oil vs minoxidil 2% for the treatment of androgenetic alopecia: a randomized comparative trial. Europe PMC 13(1):15-21.
  • Patel, DP et al. (2017). A review of the use of biotin for hair loss. Skin appendage disorders 3.3: 166-169.
  • Piacquadio DJ et al. (1994). Obesity and female androgenic alopecia: A cause and an effect? Journal of the American Academy of Dermatology 30:1028–30.
  • Rayinda T et al. (2024). Gene-environment interaction between CYP1B1 and oral contraception on frontal fibrosing alopecia. JAMA Dermatol. 160(7):732-735.
  • Saini K and Mysore V (2021). Role of vitamin D in hair loss: a short review. J Cosmet Dermatol. 20(11):3407-3414.
  • Trüeb RM (2016). Serum biotin levels in women complaining of hair loss. International journal of trichology 8.2:73.

 

PMS / PMDS

  • Agha-Hosseini et al. (2008). Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial. BJOG. 115(4):515-9.
  • Bahrami A et al. (2018). High dose vitamin D supplementation can improve menstrual problems, dysmenorrhea, and premenstrual syndrome in adolescents. Gynecol Endocrinol 34(8):659-663.
  • Beiranvand SP et al. (2016). The effect of Crocus sativus (saffron) on the severity of premenstrual syndrome, European Journal of Integrative Medicine 8(1):55-61.
  • Bertone-Johnson ER et al (2005). Calcium and vitamin D intake and risk of incident premenstrual syndrome. Arch Intern Med. 13;165(11):1246–52.
  • Chocano-Bedoya PO et al. (2011). Dietary B vitamin intake and incident premenstrual syndrome. The American Journal of Clinical Nutrition 93(5):1080–6.
  • Chocano-Bedoya P (2013). Intake of Selected Minerals and Risk of Premenstrual Syndrome. American Journal of Epidemiology 177:1118–1127.
  • Hassani N et al. (2015). Comparison of the effects of relaxation and vitamin b6 on emotional and physical symptoms in premenstrual syndrome. J Evid Based Care 5:75–83.
  • Csupor D et al. (2019). Vitex agnus-castus in premenstrual syndrome: A meta-analysis of double-blind randomised controlled trials. Complement Ther Med. 47:102190.
  • Del Mar Fernandez M et al. (2018). Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis. BMJ Open. 16;8(3):e019490.
  • Granda D et al. (2021). Is premenstrual syndrome associated with inflammation, oxidative stress and antioxidant status? A systematic review of case-control and cross-sectional studies. Antioxidants (Basel) 10(4):604.
  • Heidari H et al. (2019). Vitamin D Supplementation for Premenstrual Syndrome-Related inflammation and antioxidant markers in students with vitamin D deficient: a randomized clinical trial, Sci Rep 9(1):14939.
  • Rajabi F et al. (2020). Saffron for the Management of Premenstrual Dysphoric Disorder: A Randomized Controlled Trial. Adv Biomed Res 9:60.
  • Salehi L, Salehi F. (2007). The effect of pyridoxine (vit B6) on premenstrual syndrome. J kordestan Univ Med Sci. 2(3):32-9.
  • Shayan AAH et al. (2019). Evaluation of the effect of vitamin B6 and primrose oil on the symptoms of premenstural syndrom: Randomized clinical trial. Iran J Obstet Gynecol Infertil. 21(12). Persian.

 

Menstruationsbeschwerden

  • Alikamali M et al. (2022). The effects of vitamin E on the intensity of primary dysmenorrhea: a systematic review and meta-analysis. Clinical Nutrition Espen 52: 50-59.
  • Bahrami A et al. (2018). High dose vitamin D supplementation can improve menstrual problems, dysmenorrhea, and premenstrual syndrome in adolescents, Gynecol Endocrinol 34(8): 659-663.
  • Hudgins AP. Vitamins P, C and niacin for dysmenorrhea therapy. West J Surg & Gyn 1954;62:610-611.
  • Jafari A et al. (2011). The effect of vitamin B1 on heavy menstrual bleeding. Journal of Nutrition and Internal Medicine 2011:21(4).
  • Livdans-Forret AB et al. (2007). Menorrhagia: a synopsis of management focusing on herbal and nutritional supplements, and chiropractic. J Can Chiropr Assoc. 51(4): 235-246.
  • Pandey AK, et al. (2018). Impact of stress on female reproductive health disorders: Possible beneficial effects of shatavari (Asparagus racemosus). Biomed Pharmacother 103:46-49.
  • Parazzini F et al. (2017). Magnesium in the gynecological practice: a literature review. Magnes Res. 1;30(1):1-7.

 

Haut- und Haargesundheit

  • Barel A et al. (2005). Effect of oral intake of choline-stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Archives of Dermatological Research 297:147-153.
  • Dhaliwal S et al. (2019). Effects of zinc supplementation on inflammatory skin diseases: a systematic review of the clinical evidence.American Journal of Clinical Dermatology 21: 21-39.
  • Fatemi Naieni F et al. (2012). Serum iron, zinc, and copper concentration in premature graying of hair., Biological Trace Element Research 146(1):30-4.
  • Lee E et al. (2023). Millet seed oil activates β-catenin signaling and promotes hair growth. Front Pharmacy 14: 1172084.
  • Papakonstantinou E, Roth M and Krakiulakis G (2012): Hyaluronic acid: a key molecule in skin aging. Dermatoendocrinol 4(3): 253-258.
  • Pincemail J, Meziane S (2022). On the potential role of the antioxidant couple vitaminE/selenium taken by the oral route in skin and hair health. Antioxidants (Basel) 11(11): 2270.
  • Pullar JM, Carr AC, Vissers MCM (2017). The roles of vitamin C in skin health. Nutrients 9(8):866.
  • VanBuren CA, Everts HB (2022). Vitamin A in skin and hair: an update. Nutrients 14(14): 2952.

 

Darmgesundheit

  • Baker JM et al. (2017). Estrogen-gut microbiome axis: physiological and clinical implications. Maturitas 103:45-53.
  • Diop L et al. (2008). Probiotic Food Supplement Reduces Stress-Induced Gastrointestinal Symptoms in Volunteers: A Double-Blind, Placebo-Controlled, Randomized Trial. Nutrition Research.
  • Gibson GR (2008). Prebiotics as gut microflora management tools. J Clin Gastroenterol. 42 Suppl 2:75-9.
  • Goodarzi A et al. (2020). The potential of probiotics for treating acne vulgaris: A review of literature on acne and microbiota. Dermatologic Therapy.
  • Lee BJ, Bak YT (2011). Irritable bowel syndrome, gut microbiota and probiotics."J Neurogastroenterol Motil. 17(3):252-66.

 

Ernährung

  • Brouwer IA et al. (2010). Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans - a quantitative review. PLoS One. 5(3):e9434.
  • Buyken AE et al. (2010). Carbohydrate nutrition and inflammatory disease mortality in older adults. Am J Clin Nutr. 92(3):634-43.
  • De Souza RJ et al. (2015). Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies. BMJ. 2015 Aug 11:351:h3978.
  • Gill J. (2000). The effects of moderate alcohol consumption on female hormone levels and reproductive function. Alcohol and Alcoholism 35(5):417-423.
  • Hochrein SM et al. (2022). The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming. Cell Metabolism, https://doi.org/10.1016/j.cmet.2022.02.015.
  • Hu Y et al. (2014). Sogar-sweetened soda consumption and risk of developing rheumatoid arthritis in women. Am J Clan Nur. 100(3):959-67.
  • Jiang Y et al. (2016). A sucrose-enriched diet promotes tumorigenesis in mammary gland in part through the 12-lipoxygenase pathway. Cancer Res. 76(1):24-9.
  • Oboza P et al. (2024). Relationships between premenstrual syndrome (PMS) and diet composition, dietary patterns and eating behaviors. Nutrients 16(12), nu16121911.
  • Tin Tin S et al. (2023). Alcohol intake and endogenous sex hormones in women: meta-analysis of cohort studies and Mendelian randomization. Version 1. Res Sq. Preprint. 2023 Aug 16. doi: 10.21203/rs.3.rs-3249588/v1

 

Knochengesundheit

  • Alcantara EH et al. (2011). Diosgenin stimulates osteogenic activity by increasing bone matrix protein synthesis and bone-specific transcription factor Runx2 in osteoblastic MC3T3-E1 cells. Journal of Nutritional Biochemistry.
  • Kim S et al. (2014). Yam (Dioscorea batatas) Root and Bark Extracts Stimulate Osteoblast Mineralization by Increasing Ca and P Accumulation and Alkaline Phosphatase Activity. Preventive Nutrition and Food Science.
  • Rondanelli M et al. (2021). Essentiality of manganese for bone health: an overview and update. Natural Product Communications.

 

Blutzuckerspiegel & Diabetes

  • Cefalu WT, Hu FB. (2004). Role of chromium in human health and in diabetes. Diabetes care 27(11):2741-51.
  • Hummel J et al. (2023). Brain insulin action on peripheral insulin sensitivity in women depends on menstrual cycle phase. Nature Metabolism 5:1475-1482.

 

Kinderwunsch

  • Nasiadek M et al. (2020). The role of zink in selected female reproductive system disorders. Nutrients 12(8): 2464.
  • Ruder EH et al. (2014). Female dietary antioxidant intake and time to pregnancy among couples treated for unexplained infertility. Fertil Steril.


Schilddrüsenerkrankungen

  • Benites-Zapata VA et al. (2023). Vitamin B12 levels in thyroid disorders: a systemic review and meta-analysis. Front. Endocrinol. 14.
  • Wang F et al. (2023). Selenium and thyroid disease. Front Endocrinol (Lausanne) 14: 1133000.

 

Schwangerschaft

  • Greenberg JA et al. (2011). Folic acid supplementation and pregnancy: more than just neural tube defect prevention. Rev Obstes Gynecol. 4(2): 52-59.

 

Lebergesundheit

  • Zeisel H (1992). Choline: an important nutrient in brain development, liver function and carcinogenesis. Journal of the American College of Nutrition 11.5: 473-481.